Mosquito Gene-Drive Explorer

Héctor M. Sánchez C., Sean L. Wu, Jared Bennett, John M. Marshall
University of California, Berkeley
NCCB October 2017

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What is it?
How does it work?
Demo 1

CRISPR/CAS9 Construct Without Resistance

Demo 2

CRISPR/CAS9 Construct With Resistance

Status and Next Steps

Marshall, J., Buchman, A., C., H. M. S., & Akbari, O. S. (2017). Overcoming evolved resistance to population-suppressing homing-based gene drives. Nature Scientific Reports, (June 2017), 1–46.
Hancock, P. A., & Godfray, H. C. J. (2007). Application of the lumped age-class technique to studying the dynamics of malaria-mosquito-human interactions. Malaria Journal, 6, 98.